Need to be in direct contact with the manipulated object. 8 Furthermore, being contactlessĪlso simplifies the chip fabrication, because the transducers do not Is contactless, which is why it is suitable for so many biologicalĪpplications. Microfluidic chips, acoustofluidics, is a rapidly growing field, withĪpplications in cell and particle sorting, 1 cell patterning, 2 blood fractionation, 3, 4 droplet transport, 5 and enrichment of

Toward the acoustic manipulation of microparticles inside unstructured

The method requires no model or calibration, the work paves the way To exit the chip through one of three different outlets at will. Of this method in active sorting of particles, by guiding each particle Finally, we demonstrate the practical applications Particles simultaneously, and also a single particle in the presence That the method can be used to manipulate a single particle, three Very robust to changes in chip and particle properties. Of the field shapes, the algorithms can (eventually) move a particleįrom one position inside the chamber to another. The method learns as it goes: there is no need We show that these algorithmsĬan achieve controlled manipulation with no prior information on theĪcoustic field shapes. Transducer, based on machine-vision-measured positions of the particles.įor the control task, we propose using algorithms derived from theįamily of multi-armed bandit algorithms. Microfluidic chips, by controlling the frequency of a single ultrasound In this paper, we demonstrateĬlosed-loop two-dimensional manipulation of particles inside closed-channel However,Ĭurrent methods with a single ultrasonic transducer offer limitedĬontrol of the position of single particles. Microfluidic chips is a rapidly growing field, with applications inĬell and particle sorting, blood fractionation, droplet transport,Īnd enrichment of rare or cancerous cells, among others. Droplets, and particles via ultrasound within

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